The Effect of Exercise Training on Mental Stress-Induced Silent Ischemia
NCT00018252 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL
Last updated 2009-01-21
Summary
Coronary artery disease (CAD) remains the leading cause of death in the elderly. Silent myocardial ischemia (SI) is a manifestation of CAD in which there is a transient alteration in myocardial perfusion, function, and/or electrical activity not accompanied by chest pain. Mental and emotional stress, in particular hostility and anger are potent inducers of SI, Individuals with SI are at a 3-5 fold higher risk for the development of angina, myocardial infarction and death than subjects without SI.
Conditions
- Myocardial Ischemia
Interventions
- BEHAVIORAL
-
exercise
Sponsors & Collaborators
-
US Department of Veterans Affairs
lead FED
Study Design
- Allocation
- RANDOMIZED
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1997-04-30
- Completion
- 2000-03-31
Countries
- United States
Study Locations
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