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Epidemiology of Surfactant Protein-B Deficiency

NCT00014859 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5176

Last updated 2024-04-29

No results posted yet for this study

Summary

The purpose of this study is to test the hypothesis that excess, rare, functionally disruptive single nucleotide polymorphisms (SNPs) characterize genes (e.g., the surfactant protein-B gene)(SFTPB) and gene networks (e.g., the pulmonary surfactant metabolic network or other gene networks that regulate alveolar type 2 cell function) associated with increased risk of neonatal respiratory distress syndrome (RDS).

Conditions

  • Lung Diseases
  • Respiratory Distress Syndrome, Newborn
  • Pulmonary Surfactant
  • Lung Diseases, Interstitial

Sponsors & Collaborators

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • F. Sessions Cole, MD · Washington University School of Medicine

Eligibility

Max Age
1 Year
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-06-01
Primary Completion
2024-04-26
Completion
2024-04-26

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00014859 on ClinicalTrials.gov