Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate Cancer
NCT00014352 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-01-16
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Anticoagulant drugs such as warfarin may reduce the risk of blood clots.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus warfarin in treating patients who have prostate cancer.
Conditions
- Prostate Cancer
- Thromboembolism
Interventions
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
estramustine phosphate sodium
- DRUG
-
ketoconazole
- DRUG
-
warfarin
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
William K. Kelly, DO · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-09-30
- Primary Completion
- 2003-03-31
Countries
- United States
Study Locations
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