Protection Against Benzene Toxicity
NCT00011453 · Status: COMPLETED · Type: OBSERVATIONAL
Last updated 2005-06-24
Summary
We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.
Conditions
- Leukemia
- Aplastic Anemia
Sponsors & Collaborators
-
National Institute of Environmental Health Sciences (NIEHS)
lead NIH
Eligibility
- Min Age
- 21 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1998-07-31
- Completion
- 2001-06-30
Countries
- United States
Study Locations
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