Fulvestrant in Treating Patients With Recurrent, Persistent, or Metastatic Endometrial Cancer
NCT00006903 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 67
Last updated 2019-03-20
Summary
This phase II trial is studying fulvestrant to see how well it works in treating patients with recurrent, persistent, or metastatic endometrial cancer. Estrogen can stimulate the growth of cancer cells. Hormone therapy using fulvestrant may fight cancer by blocking the uptake of estrogen by the tumor cells.
Conditions
- Recurrent Uterine Corpus Carcinoma
- Stage III Uterine Corpus Cancer AJCC v7
- Stage IV Uterine Corpus Cancer AJCC v7
Interventions
- DRUG
-
Given intramuscularly
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Gynecologic Oncology Group
lead NETWORK
Principal Investigators
-
Allan L Covens · NRG Oncology
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-08-30
- Primary Completion
- 2008-03-17
More Related Trials
-
Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer
NCT03643510 ·Status: COMPLETED ·Phase: PHASE2
-
Fertility-sparing Management Using High-dose Oral Progestin in Young Women With Endometrial Cancer
NCT03567655 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Ovarian Epithelial Cancer
NCT00005612 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer
NCT03348631 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Fulvestrant Plus Abemaciclib in Women With Advanced Low Grade Serous Carcinoma
NCT03531645 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer
NCT00004251 ·Status: COMPLETED ·Phase: PHASE2
-
Raloxifene in Treating Patients With Persistent or Recurrent Endometrial Cancer
NCT00004915 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer
NCT00003413 ·Status: COMPLETED ·Phase: PHASE2
-
Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer
NCT00132067 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With Recurrent, Stage III, or Stage IV Endometrial Cancer
NCT00016341 ·Status: TERMINATED ·Phase: PHASE3
-
Mifepristone in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
NCT00459290 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Study on Fasudil Hydrochloride for Treatment of Gene-Specific Ovarian Cancer
NCT06890858 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
NCT06979596 ·Status: RECRUITING ·Phase: PHASE2
-
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer or Primary Peritoneal Cancer
NCT00003136 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
RO4929097 in Treating Patients With Recurrent and/or Metastatic Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
NCT01175343 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2 Study of PI3K Inhibitor Copanlisib in Combination With Fulvestrant in Selected ER+ and/or PR+ Cancers With PI3K (PIK3CA, PIK3R1) and/or PTEN Alterations
NCT05082025 ·Status: TERMINATED ·Phase: PHASE2
-
Capecitabine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT00004012 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
NCT03660826 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
FR901228 in Treating Patients With Relapsed or Refractory Advanced Ovarian Epithelial Cancer
NCT00085527 ·Status: WITHDRAWN ·Phase: PHASE2
-
Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission
NCT00522301 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Vintafolide (MK-8109, EC145) in Participants With Advanced Ovarian and Endometrial Cancers (MK-8109-007, EC-FV-02)
NCT00507741 ·Status: COMPLETED ·Phase: PHASE2
-
Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal Cancer
NCT00026091 ·Status: COMPLETED ·Phase: PHASE2
-
RAD001 in Recurrent Endometrial Cancer Patients
NCT00087685 ·Status: COMPLETED ·Phase: PHASE2
-
Irofulven in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer
NCT00019552 ·Status: COMPLETED ·Phase: PHASE2
-
S9720 Combination Chemotherapy in Treating Patients With Metastatic, Recurrent, or Refractory Endometrial Cancer
NCT00003127 ·Status: COMPLETED ·Phase: PHASE2