Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer
NCT00132067 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2019-07-23
Summary
This phase II trial is studying how well vorinostat works in treating patients with recurrent or persistent ovarian epithelial or primary peritoneal cavity cancer. Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Conditions
- Primary Peritoneal Cavity Cancer
- Recurrent Ovarian Epithelial Cancer
Interventions
- DRUG
-
vorinostat
Given orally
Sponsors & Collaborators
-
Gynecologic Oncology Group
collaborator NETWORK -
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Susan Modesitt · Gynecologic Oncology Group
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-10-31
- Primary Completion
- 2006-08-31
- Completion
- 2008-07-31
Countries
- United States
Study Locations
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