A Study of the Safety and Effectiveness of an HIV Vaccine for HIV-Positive Patients Receiving Anti-HIV Drugs for at Least 2 Years
NCT00006509 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2015-03-09
Summary
The purpose of this study is to see if 2 study vaccines, ALVAC-HIV (vCP1452) and gp160 MN/LAI-2, are safe and effective in boosting the body's attacks on HIV in HIV-positive patients.
HIV-infected patients who have been treated with anti-HIV drugs for a long time may have weakened immune responses. One way to strengthen these responses may be to have a safe and effective vaccine, which will boost immune responses that are specific to HIV.
Conditions
- HIV Infections
Interventions
- BIOLOGICAL
-
ALVAC(2)120(B,MN)GNP (vCP1452)
- BIOLOGICAL
-
gp160 MN/LAI-2
Sponsors & Collaborators
-
National Institute of Allergy and Infectious Diseases (NIAID)
lead NIH
Principal Investigators
-
David Ho
-
Martin Markowitz
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Completion
- 2007-06-30
Countries
- United States
Study Locations
More Related Trials
-
Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV
NCT00056797 ·Status: COMPLETED ·Phase: PHASE2
-
HIV Candidate Vaccine, ALVAC-HIV-1, Administration in HIV-Negative Adults
NCT00013572 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Effectiveness of Anti-HIV Vaccines in HIV-Negative Adults
NCT00000904 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Test the Safety of Three Experimental HIV Vaccines
NCT00000946 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Immune Response Study of High-Dose Canarypox ALVAC-HIV Vaccine in Healthy, HIV Uninfected Adults
NCT00027261 ·Status: COMPLETED ·Phase: PHASE1
-
Immune Responses in HIV-Positive Patients Receiving an Anti-HIV Drug Combination When Given the HIV Vaccines Remune and vCP1452
NCT00006495 ·Status: COMPLETED ·Phase: PHASE1
-
Effectiveness of Giving an HIV Vaccine (Remune) to HIV-Positive Patients Receiving an Anti-HIV Drug Combination
NCT00005758 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3
NCT00000755 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Immune Response Study of the Vaccine ALVAC vCP1452 Alone or in Combination With AIDSVAX B/B
NCT00007332 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African Adults
NCT00415649 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Effectiveness of Administering an HIV Vaccine in the Groin Versus the Arm
NCT00076817 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Boosting Strategies After Vaccination With ALVAC-HIV and AIDSVAX® B/E
NCT01931358 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
NCT03284710 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Safety, Tolerability and Immunogenicity of a 1-Dose Regimen of MRKAd5 HIV-1 Gag Vaccine Versus the ALVAC_HIV Vaccine (V520-019)
NCT00894114 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety and Immune Response Study of 2 Experimental HIV Vaccines
NCT02404311 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluating the Safety and Immunogenicity of an HIV Vaccine (gp145 C.6980) in Healthy, HIV-Uninfected Adults in the United States
NCT03382418 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Safety and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults Who Have Participated in Previous HIV Vaccine Clinical Trials and in Adults Who Have Not Participated in Previous HIV Vaccine Clinical Trials
NCT01376726 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Comparative Blinded Trial of Several HIV-1 Derived Immunogens in Infected Individuals With >= 500 CD4 Cells/mm3
NCT00000779 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Treatment for HIV-Infection
NCT00108654 ·Status: COMPLETED ·Phase: PHASE1
-
Immunogenicity and Safety of 2 Schedules of ALVAC-HIV vCP1452 in Chronically HIV-Infected Patients
NCT00219362 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Safety and Immunogenicity of ALVAC-HIV and MF59®- or AS01B-adjuvanted Bivalent Subtype C gp120 in Healthy, HIV-uninfected Adult Participants
NCT03122223 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of MN Recombinant Soluble gp120/HIV-1 (rsgp120/HIV-1) (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults
NCT00001052 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Safety Study of Two Experimental HIV Vaccines
NCT00479999 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Late Boost Strategies for HIV-uninfected Participants From Protocol RV 144
NCT01435135 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of rgp120/HIV-1MN (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults.
NCT00001044 ·Status: COMPLETED ·Phase: PHASE1