Combination Chemotherapy in Treating Patients With Stage II or Stage III Multiple Myeloma
NCT00006232 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2013-05-15
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective for multiple myeloma.
PURPOSE: This randomized phase III trial is comparing two combination chemotherapy regimens to see how well they work in treating patients with stage II or stage III multiple myeloma.
Conditions
- Multiple Myeloma and Plasma Cell Neoplasm
Interventions
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
idarubicin
- DRUG
-
vincristine sulfate
Sponsors & Collaborators
-
West of Scotland Lymphoma Group
lead OTHER
Principal Investigators
-
Gordon Cook, MD, PhD · Leeds Cancer Centre at St. James's University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1996-10-31
- Completion
- 2007-08-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
IFM 2005-01: Velcade/Dexamethasone Versus Vincristine/Adriamycin (Doxorubicin)/Dexamethasone (VAD) for the Treatment of Patients With Multiple Myeloma
NCT00200681 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Study of Velcade, Decadron, and Doxil Followed by Cyclophosphamide in Multiple Myeloma
NCT00148317 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Multiple Myeloma
NCT00002678 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Combination Therapy With VELCADE, Doxil, and Dexamethasone (VDd) in Multiple Myeloma
NCT00135187 ·Status: COMPLETED ·Phase: NA
-
S0232 Dexamethasone With or Without Lenalidomide in Treating Patients With Previously Untreated Stage I, Stage II, or Stage III Multiple Myeloma
NCT00064038 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess Two Different Strategies of Combining Dexamethasone and VELCADE
NCT00063791 ·Status: NO_LONGER_AVAILABLE
-
A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatment
NCT02951117 ·Status: WITHDRAWN ·Phase: PHASE1
-
PAD. ICORG 05-01, V11
NCT00814541 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma
NCT00002653 ·Status: UNKNOWN ·Phase: PHASE3
-
Pegylated Liposomal Doxorubicin Hydrochloride, Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Multiple Myeloma
NCT00849251 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Alternative Schedule of Velcade/Dexamethasone Plus Doxil for Patients With Multiple Myeloma
NCT00366106 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate Two Different Regimens of VELCADE in Combination With Dexamethasone, Thalidomide and Cyclophosphamide (VDT vs VDTC) in Newly Diagnosed Multiple Myeloma
NCT00531453 ·Status: COMPLETED ·Phase: PHASE2
-
Dexamethasone and Chemotherapy With or Without Plasma Exchange in Patients With Newly Diagnosed Multiple Myeloma and Acute Kidney Failure
NCT00416897 ·Status: COMPLETED ·Phase: PHASE3
-
Thalidomide, Doxorubicin, and Dexamethasone in Treating Patients With Untreated Stage II or Stage III Multiple Myeloma
NCT00008242 ·Status: COMPLETED ·Phase: PHASE2
-
Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
NCT00033332 ·Status: COMPLETED ·Phase: PHASE3
-
Pomalidomide and Dexamethasone With or Without Ixazomib in Treating Patients With Relapsed Multiple Myeloma
NCT02004275 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Velcade (Bortezomib), Adriamycin Dexamethasone (PAD) or Vincristine Adriamycin Dexamethasone in Second Line Treatment of Multiple Myeloma
NCT00441168 ·Status: TERMINATED ·Phase: PHASE2
-
Bortezomib, Doxorubicin Hydrochloride Liposome, and Thalidomide as First-line Therapy in Treating Patients With Previously Untreated Stage I, II, or III Multiple Myeloma
NCT00523848 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse
NCT06948084 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Daratumumab, Bortezomib, and Dexamethasone With or Without Venetoclax in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT03701321 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Velcade, Doxil, and Dexamethasone (VDd) as First Line Therapy for Multiple Myeloma
NCT00116961 ·Status: COMPLETED ·Phase: PHASE2
-
Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma
NCT06169215 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Bortezomib and Dexamethasone in Treating Patients With Multiple Myeloma That Has Relapsed or Has Not Responded to Treatment
NCT00389701 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Efficacy of Treatment With Bortezomib (in Combination With Doxorubicin and Dexamethasone) in Previously Untreated Patients With Multiple Myeloma
NCT00872521 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Subcutaneous and Intravenous Velcade in Combination With Dexamethasone in Chinese Subjects With Relapsed and Refractory Multiple Myeloma
NCT02811978 ·Status: COMPLETED ·Phase: PHASE3