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Decompression Intervention of Variceal Rebleeding Trial (DIVERT)

NCT00006161 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2010-01-13

No results posted yet for this study

Summary

The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center prospective randomized clinical trial comparing the radiologic procedure of transjugular intrahepatic portal-systemic shunt (TIPS) with the surgical procedure of distal splenorenal shunt (DSRS) for variceal bleeding in patients with Child's Class A and B cirrhosis.

This is recognized nationally and internationally as the study that will answer the question as to which of these is the best treatment for decompression of varices in patients who have failed endoscopic and pharmacologic therapy.

Conditions

Interventions

PROCEDURE

Transjugular Intrahepatic Portosystemic Shunt (TIPS)

PROCEDURE

Distal Splenorenal Shunt

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    lead NIH

Principal Investigators

  • J. Michael Henderson, M.D. · The Cleveland Clinic

  • Thomas D. Boyer, M.D. · Emory University

  • Lennox Jeffers, M.D. · University of Miami

  • Enrique Molina, M.D. · University of Miami

  • Layton F. Rikkers, M.D. · University of Wisconsin, Madison

  • Kareem Abu-Elmagd, M.D. · University of Pittsburgh Medical Center

  • Amrik Shah, Sc.D. · Cleveland Clinic Foundation - Data Coordinating Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1996-12-31
Completion
2003-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00006161 on ClinicalTrials.gov