Perifosine in Treating Patients With Advanced Solid Tumors
NCT00005794 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2019-12-13
Summary
RATIONALE: Perifosine may stop the growth of tumor cells by stopping blood flow to the tumor.
PURPOSE: Phase I trial to study the effectiveness of perifosine in treating patients who have advanced solid tumors.
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
perifosine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
Lynn Van Ummersen, MD · University of Wisconsin, Madison
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-02-29
- Completion
- 2003-07-31
Countries
- United States
Study Locations
More Related Trials
-
Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer
NCT01497925 ·Status: COMPLETED ·Phase: PHASE1
-
Benzoylphenylurea in Treating Patients With Advanced Cancer
NCT00010205 ·Status: TERMINATED ·Phase: PHASE1
-
A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer Patients
NCT00728468 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Trial of Continuous Infusion UCN-01 in Patients With Refractory Neoplasms
NCT00001444 ·Status: COMPLETED ·Phase: PHASE1
-
An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
NCT04733534 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer
NCT03459729 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies
NCT03199586 ·Status: COMPLETED ·Phase: PHASE1
-
Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy
NCT00077064 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of [14 C]-Pevonedistat in Participants With Advanced Solid Tumors
NCT03057366 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Study of Porfiromycin in Head and Neck Cancer and Other Cancer Patients With Solid Tumors
NCT02209701 ·Status: TERMINATED ·Phase: PHASE1
-
Epoetin Alfa in Treating Fatigue in Patients With Advanced Solid Tumors Who Are Not Receiving Chemotherapy
NCT00052221 ·Status: WITHDRAWN ·Phase: NA
-
Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors
NCT00387504 ·Status: COMPLETED ·Phase: PHASE1
-
The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC
NCT04170959 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Effects of Rifampin on Pharmacokinetics (PK) of Pevonedistat in Participants With Advanced Solid Tumors
NCT03486314 ·Status: COMPLETED ·Phase: PHASE1
-
AFP464 in Treating Patients With Advanced Solid Tumors
NCT00369200 ·Status: TERMINATED ·Phase: PHASE1
-
Docetaxel in Treating Older Patients With Metastatic Breast, Lung, or Prostate Cancer
NCT00059943 ·Status: COMPLETED ·Phase: PHASE2
-
Perillyl Alcohol in Treating Patients With Refractory Cancer
NCT00002862 ·Status: COMPLETED ·Phase: PHASE1
-
Study of 124I-NM404 in Advanced Solid Malignancies
NCT01662284 ·Status: TERMINATED
-
Efficacy and Safety of Decitabine Plus CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma
NCT03553537 ·Status: UNKNOWN ·Phase: PHASE3
-
Fentanyl Pectin Nasal Spray (FNPS) for Exercise-Induced Breakthrough Dyspnea
NCT01832402 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of a Cell Penetrating Peptide (p28) to Treat Solid Tumors That Resist Standard Methods of Treatment
NCT00914914 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors
NCT00570284 ·Status: COMPLETED ·Phase: PHASE1
-
Polyglutamate Camptothecin in Treating Patients With Advanced Cancer
NCT00059917 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Immunogenicity and Pharmacokinetics of ONC-841
NCT06219499 ·Status: WITHDRAWN ·Phase: PHASE1
-
Combretastatin A4 Phosphate in Treating Patients With Advanced Solid Tumors
NCT00003768 ·Status: COMPLETED ·Phase: PHASE1