Study of Systemic Amyloidosis Presentation and Prognosis
NCT00004374 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2005-06-24
Summary
OBJECTIVES: I. Analyze prospectively the course of amyloid deposition in patients with primary, secondary, myeloma-associated, and hereditary amyloidosis.
II. Determine abnormalities of humoral and delayed-type hypersensitivity in these patients.
III. Identify prognostic factors in hereditary amyloidosis and develop tests for genetic defects associated with systemic amyloidosis.
IV. Diagnose familial amyloidotic polyneuropathy (FAP) prior to symptom onset. V. Validate the correlation of low serum prealbumin and retinol binding protein levels with amyloidosis in patients with FAP.
Conditions
- Amyloidosis
Sponsors & Collaborators
-
Indiana University School of Medicine
collaborator OTHER -
National Center for Research Resources (NCRR)
lead NIH
Principal Investigators
-
Merrill D. Benson · Indiana University School of Medicine
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1979-01-31
Countries
- United States
Study Locations
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