Study of Systemic Amyloidosis Presentation and Prognosis

NCT00004374 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2005-06-24

No results posted yet for this study

Summary

OBJECTIVES: I. Analyze prospectively the course of amyloid deposition in patients with primary, secondary, myeloma-associated, and hereditary amyloidosis.

II. Determine abnormalities of humoral and delayed-type hypersensitivity in these patients.

III. Identify prognostic factors in hereditary amyloidosis and develop tests for genetic defects associated with systemic amyloidosis.

IV. Diagnose familial amyloidotic polyneuropathy (FAP) prior to symptom onset. V. Validate the correlation of low serum prealbumin and retinol binding protein levels with amyloidosis in patients with FAP.

Conditions

  • Amyloidosis

Sponsors & Collaborators

  • Indiana University School of Medicine

    collaborator OTHER
  • National Center for Research Resources (NCRR)

    lead NIH

Principal Investigators

  • Merrill D. Benson · Indiana University School of Medicine

Eligibility

Min Age
0 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1979-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004374 on ClinicalTrials.gov