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Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

NCT00004361 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2005-06-24

No results posted yet for this study

Summary

OBJECTIVES: I. Identify latent hypoparathyroidism in normocalcemic adult survivors with repaired conotruncal cardiac defects, by evaluating parathyroid gland secretory function after induced hypocalcemia.

II. Determine the relationship of parathyroid hormone secretion to microdeletions in the same region of chromosome 22q11 as found in patients with DiGeorge anomaly.

Conditions

  • Hypoparathyroidism
  • Tetralogy of Fallot
  • Pulmonary Valve Stenosis
  • Conotruncal Cardiac Defects
  • Heart Defects, Congenital
  • Pulmonary Atresia

Interventions

DRUG

calcium gluconate

DRUG

sodium citrate

Sponsors & Collaborators

  • National Center for Research Resources (NCRR)

    lead NIH

  • Ann & Robert H Lurie Children's Hospital of Chicago

    collaborator OTHER

Principal Investigators

  • Craig B. Langman · Ann & Robert H Lurie Children's Hospital of Chicago

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1995-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004361 on ClinicalTrials.gov