Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia
NCT00004323 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2005-06-24
Summary
OBJECTIVES: I. Evaluate the efficacy of related, HLA-identical bone marrow transplantation following cyclophosphamide (CTX) and antithymocyte globulin in patients with aplastic anemia.
II. Evaluate the efficacy of related, HLA-nonidentical bone marrow transplantation following CTX and total-body irradiation/total-lymphoid irradiation in patients with aplastic anemia.
Conditions
- Aplastic Anemia
Interventions
- DRUG
-
anti-thymocyte globulin
- DRUG
- DRUG
-
cyclosporine
- DRUG
-
mesna
- DRUG
-
methotrexate
- DRUG
-
methylprednisolone
Sponsors & Collaborators
-
University of California, Los Angeles
collaborator OTHER -
National Center for Research Resources (NCRR)
lead NIH
Principal Investigators
-
Mary Carol Territo · University of California, Los Angeles
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 0 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1995-02-28
Countries
- United States
Study Locations
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