Bryostatin 1 Plus Gemcitabine in Treating Patients With Advanced Cancer
NCT00004144 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2014-04-24
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of bryostatin 1 plus gemcitabine in treating patients who have advanced cancer that has not responded to previous treatment.
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
bryostatin 1
- DRUG
-
gemcitabine hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Barbara Ann Karmanos Cancer Institute
lead OTHER
Principal Investigators
-
Philip A. Philip, MD, PhD, FRCP · Barbara Ann Karmanos Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-05-31
- Primary Completion
- 2006-12-31
- Completion
- 2006-12-31
Countries
- United States
Study Locations
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