Irinotecan and Capecitabine in Treating Patients With Solid Tumors
NCT00003867 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2018-09-10
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of irinotecan and capecitabine in treating patients who have solid tumors that have not responded to previous treatment.
Conditions
Interventions
- DRUG
- DRUG
-
irinotecan hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Montefiore Medical Center
lead OTHER
Principal Investigators
-
Sridhar Mani, MD · Albert Einstein College of Medicine
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-03-31
- Primary Completion
- 2003-03-31
- Completion
- 2003-03-31
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma
NCT00077285 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery
NCT00576654 ·Status: COMPLETED ·Phase: PHASE1
-
7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)
NCT00031681 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors
NCT00112892 ·Status: COMPLETED ·Phase: PHASE1
-
Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies
NCT01705106 ·Status: TERMINATED ·Phase: PHASE1
-
Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
NCT00003776 ·Status: COMPLETED ·Phase: PHASE2
-
Ixabepilone and Ketoconazole in Treating Patients With Advanced Solid Tumors
NCT00096317 ·Status: COMPLETED ·Phase: PHASE1
-
Ifosfamide and Topotecan in Treating Patients With Refractory Solid Tumors
NCT00003198 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Therapy in Cancers With Mutations in DNA Repair Genes
NCT05694715 ·Status: RECRUITING ·Phase: PHASE1
-
Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer
NCT00004065 ·Status: COMPLETED ·Phase: PHASE1
-
CP-609,754 in Treating Patients With Advanced Solid Tumors
NCT00006085 ·Status: UNKNOWN ·Phase: PHASE1
-
BMS-188797 and Carboplatin in Treating Patients With Advanced Nonhematologic Cancer
NCT00006086 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer
NCT00100828 ·Status: TERMINATED ·Phase: PHASE2
-
Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT00103259 ·Status: COMPLETED ·Phase: PHASE2
-
Erlotinib in Treating Patients With Metastatic and/or Recurrent Head and Neck Cancer
NCT00281866 ·Status: COMPLETED ·Phase: PHASE2
-
Erlotinib and Bevacizumab in Treating Patients With Stage IV Melanoma
NCT00466687 ·Status: COMPLETED ·Phase: PHASE2
-
Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
NCT01375829 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
NCT06541262 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Sorafenib and Bortezomib in Treating Patients With Advanced Cancer
NCT00303797 ·Status: COMPLETED ·Phase: PHASE1
-
CP4071 in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
NCT00017446 ·Status: UNKNOWN ·Phase: PHASE2
-
Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor
NCT01189643 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00368914 ·Status: COMPLETED ·Phase: PHASE1
-
Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors
NCT00892385 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I/II Study of High-Dose Calcitriol Plus Temodar for Patients With Metastatic Melanoma
NCT00301067 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
NCT00335764 ·Status: COMPLETED ·Phase: PHASE1/PHASE2