VX-710, Doxorubicin, and Vincristine for the Treatment of Patients With Recurrent Small Cell Lung Cancer
NCT00003847 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2013-09-05
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy for the treatment of patients who have recurrent small cell lung cancer following treatment.
Conditions
Interventions
- DRUG
-
biricodar dicitrate
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
vincristine sulfate
Sponsors & Collaborators
-
Vertex Pharmaceuticals Incorporated
lead INDUSTRY
Principal Investigators
-
Matthew Harding, PhD · Vertex Pharmaceuticals Incorporated
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-12-31
- Primary Completion
- 2001-02-28
Countries
- United States
Study Locations
More Related Trials
-
Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer
NCT00687297 ·Status: COMPLETED ·Phase: PHASE2
-
Vorinostat, Carboplatin, and Paclitaxel in Treating Patients With Advanced or Metastatic Non-Small Cell Lung Cancer
NCT00481078 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan and Vinorelbine in Treating Patients With Recurrent Lung Cancer
NCT00287963 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancer
NCT02566993 ·Status: COMPLETED ·Phase: PHASE3
-
Docetaxel & Oxaliplatin in Combination With Bevacizumab as First-Line Treatment in Subjects With Non-Small Cell Lung Cancer (NSCLC)
NCT00356122 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer
NCT02117024 ·Status: TERMINATED ·Phase: PHASE2
-
Docetaxel and Vinorelbine Plus Filgrastim in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00006215 ·Status: UNKNOWN ·Phase: PHASE2
-
A Clinical Trial of Vorinostat (MK0683, SAHA) in Combination With FDA Approved Cancer Drugs in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)(0683-056)
NCT00473889 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
VNP40101M in Treating Patients With Relapsed or Refractory Locally Advanced or Metastatic Small Cell Lung Cancer
NCT00282022 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer
NCT00856037 ·Status: COMPLETED ·Phase: PHASE1
-
Suramin, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00006929 ·Status: COMPLETED ·Phase: PHASE2
-
Inhaled Doxorubicin Plus IV Docetaxel and Cisplatin in Patients With Non-Small-Cell Lung Carcinoma (NSCLC)
NCT00082472 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Docetaxel (Taxotere), Vinorelbine, and Bevacizumab, as Adjuvant Chemotherapy for Patients With Resected Stage I-III Non-small Cell Lung Cancer
NCT00675597 ·Status: COMPLETED ·Phase: NA
-
Carboplatin, Paclitaxel, Bevacizumab and Vorinostat for Patients With Advanced Non-Small Cell Lung Cancer
NCT00702572 ·Status: TERMINATED ·Phase: PHASE1
-
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression
NCT04274907 ·Status: TERMINATED ·Phase: PHASE1
-
Vinorelbine, Gemcitabine, and Docetaxel Compared With Paclitaxel and Carboplatin in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT00079287 ·Status: COMPLETED ·Phase: PHASE3
-
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
NCT00003281 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
NCT00004126 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line Treatment
NCT01497041 ·Status: UNKNOWN ·Phase: PHASE2
-
S9806: Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00003587 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy as Induction Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
NCT00003037 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLC
NCT00697476 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study Evaluating the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Adults With Stage III Non-Small Cell Lung Cancer (NSCLC)
NCT02412371 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Docetaxel - Carboplatin As Second Line Treatment in Patients with Small Cell Lung Cancer
NCT00686985 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Paclitaxel, Carboplatin, and Gemcitabine Versus Gemcitabine and Vinorelbine for Non-Small Cell Lung Cancer
NCT00193362 ·Status: COMPLETED ·Phase: PHASE3