Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00003409 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2009-02-09
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Motexafin gadolinium may increase the effectiveness of radiation therapy by making tumor cells more sensitive to radiation.
PURPOSE: Phase I trial to study the effectiveness of motexafin gadolinium plus radiation therapy in treating patients who have newly diagnosed glioblastoma multiforme.
Conditions
Interventions
- DRUG
-
motexafin gadolinium
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Judith M. Ford, MD, PhD · Jonsson Comprehensive Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-07-31
Countries
- United States
Study Locations
More Related Trials
-
Motexafin Gadolinium Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma
NCT00003909 ·Status: COMPLETED ·Phase: PHASE1
-
Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
NCT00305864 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases
NCT00121420 ·Status: TERMINATED ·Phase: PHASE2
-
Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma
NCT00387790 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases
NCT00003563 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas
NCT00080054 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme
NCT00006388 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy in Treating Patients With Glioblastoma
NCT00019058 ·Status: COMPLETED ·Phase: PHASE1
-
Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme
NCT00003417 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00869401 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma
NCT04477200 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Radiation Boost for Newly Diagnosed Glioblastoma Multiforme
NCT00376103 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
NCT00052208 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma
NCT00357253 ·Status: COMPLETED ·Phase: PHASE1
-
Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma
NCT00841555 ·Status: COMPLETED ·Phase: PHASE1
-
Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas
NCT00042991 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme
NCT00006386 ·Status: COMPLETED ·Phase: PHASE2
-
Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00004073 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
NCT00253448 ·Status: COMPLETED ·Phase: PHASE2
-
Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM
NCT00548938 ·Status: TERMINATED ·Phase: PHASE2
-
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
NCT02709226 ·Status: COMPLETED ·Phase: PHASE1
-
Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00128700 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00099125 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00003996 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma
NCT00514397 ·Status: UNKNOWN ·Phase: PHASE2