Biological Therapy in Treating Patients With Primary or Advanced Glioma
NCT00003067 · Status: SUSPENDED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2009-02-09
Summary
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells in patients with primary or advanced glioma.
PURPOSE: Clinical trial to study the effectiveness of biological therapy with interleukin-2 and lymphokine-activated killer cells in treating patients who have primary, recurrent, or refractory malignant glioma.
Conditions
Interventions
- BIOLOGICAL
-
aldesleukin
- BIOLOGICAL
-
lymphokine-activated killer cells
Sponsors & Collaborators
-
Weill Medical College of Cornell University
lead OTHER
Principal Investigators
-
Roberta L. Hayes, PhD · Immune Therapy, LLC
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-07-31
Countries
- United States
Study Locations
More Related Trials
-
Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma
NCT00730613 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Malignant Glioma
NCT00068510 ·Status: COMPLETED ·Phase: PHASE1
-
Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma
NCT03072134 ·Status: COMPLETED ·Phase: PHASE1
-
Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma
NCT00058123 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Therapy in Treating Patients With Glioblastoma Multiforme
NCT00003185 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
NCT01082926 ·Status: COMPLETED ·Phase: PHASE1
-
Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma
NCT06557512 ·Status: RECRUITING ·Phase: NA
-
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma
NCT01290692 ·Status: COMPLETED ·Phase: PHASE2
-
IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma
NCT00003842 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma
NCT02026271 ·Status: COMPLETED ·Phase: PHASE1
-
Immunotoxin Therapy in Treating Patients With Malignant Glioma
NCT00006268 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)
NCT02924038 ·Status: TERMINATED ·Phase: PHASE1
-
Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy
NCT00679354 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
NCT02010606 ·Status: COMPLETED ·Phase: PHASE1
-
Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma
NCT04729959 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma
NCT02208362 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
NCT04732065 ·Status: RECRUITING ·Phase: PHASE1
-
Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma
NCT00036972 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
NCT02709226 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors
NCT03163368 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
NCT01188096 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma
NCT01081223 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Malignant Glioma
NCT00612001 ·Status: COMPLETED ·Phase: PHASE1
-
Stereotactic Radiosurgery in Treating Patients With Brain Tumors
NCT00019578 ·Status: COMPLETED ·Phase: PHASE1
-
Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid
NCT00241670 ·Status: COMPLETED ·Phase: PHASE3