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Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer

NCT00003063 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1050

Last updated 2013-09-20

No results posted yet for this study

Summary

RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy with biological therapy may kill more tumor cells.

PURPOSE: Randomized phase III trial to compare the effectiveness of treatment using levamisole with treatment using interferon alfa and combination chemotherapy consisting of fluorouracil and leucovorin in patients with stage II or stage III colorectal cancer.

Conditions

Interventions

BIOLOGICAL

recombinant interferon alfa

DRUG

fluorouracil

DRUG

leucovorin calcium

DRUG

levamisole hydrochloride

Sponsors & Collaborators

  • European Institute of Oncology

    lead OTHER

Principal Investigators

  • Francesco Tonelli, MD · Universita Degli Studi di Florence - Policlinico di Careggi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1991-11-30

Countries

  • Greece
  • Italy
  • South Korea

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00003063 on ClinicalTrials.gov