Bryostatin 1 in Treating Patients With Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00002908 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-04-05
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness of bryostatin 1 in treating patients who have relapsed non-Hodgkin's lymphoma or chronic lymphocytic leukemia.
Conditions
Interventions
- DRUG
-
bryostatin 1
- DRUG
-
vincristine sulfate
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Barbara Ann Karmanos Cancer Institute
lead OTHER
Principal Investigators
-
Ayad M. Al-Katib, MD, FACP · Barbara Ann Karmanos Cancer Institute
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1996-12-31
- Primary Completion
- 2000-02-29
- Completion
- 2001-11-30
Countries
- United States
Study Locations
More Related Trials
-
Etoposide in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
NCT00002880 ·Status: COMPLETED ·Phase: PHASE2
-
Bryostatin 1 and Interleukin-2 in Treating Patients With Refractory Solid Tumors or Lymphoma
NCT00003993 ·Status: COMPLETED ·Phase: PHASE1
-
Epirubicin and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00062296 ·Status: COMPLETED ·Phase: PHASE2
-
Investigation of Safety, Tolerability and Maximum Tolerated Dose (MTD) of BI 2536 in Patients With Recurrent Advanced Aggressive Non-Hodgkin's Lymphoma (NHL)
NCT00243087 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
NCT00006125 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma
NCT02824029 ·Status: COMPLETED ·Phase: PHASE2
-
Vorinostat and Combination Chemotherapy Before Donor Stem Cell Transplantation for the Treatment of Relapsed Aggressive B-cell or T-cell Non-Hodgkin Lymphoma
NCT04220008 ·Status: WITHDRAWN ·Phase: PHASE2
-
Liposomal Vincristine in Treating Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma
NCT00006383 ·Status: COMPLETED ·Phase: PHASE2
-
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas
NCT03925428 ·Status: WITHDRAWN ·Phase: PHASE1
-
Vorinostat in Treating Patients With Relapsed or Refractory Advanced Hodgkin's Lymphoma
NCT00132028 ·Status: COMPLETED ·Phase: PHASE2
-
Buparlisib in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
NCT01719250 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment
NCT05627245 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
NCT00002494 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies
NCT00691210 ·Status: COMPLETED ·Phase: PHASE1
-
CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
NCT02168140 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
NCT00003388 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma
NCT00003245 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of MDX-060 in Subjects With Relapsed or Refractory Hodgkin's Disease
NCT00284804 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma
NCT00006029 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma
NCT00053105 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of MDX-1203 in Subjects With Advanced/Recurrent Clear Cell Renal Cell Carcinoma (ccRCC) or Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL)
NCT00944905 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma
NCT02309580 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia
NCT03136146 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma
NCT01258998 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Cisplatin, and Dexamethasone in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma
NCT00090909 ·Status: COMPLETED ·Phase: PHASE2