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Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma

NCT00002764 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 340

Last updated 2012-07-11

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether surgery plus combination chemotherapy is more effective than surgery alone in treating patients with lung metastases from soft tissue sarcoma.

PURPOSE: Randomized phase III trial to compare the effectiveness of surgery plus combination chemotherapy with that of surgery alone in treating patients who have soft tissue sarcoma that has spread to the lung.

Conditions

Interventions

BIOLOGICAL

filgrastim

DRUG

doxorubicin hydrochloride

DRUG

ifosfamide

PROCEDURE

conventional surgery

Sponsors & Collaborators

  • Eastern Cooperative Oncology Group

    collaborator NETWORK

  • Scandinavian Sarcoma Group

    collaborator OTHER

  • SWOG Cancer Research Network

    collaborator NETWORK

  • European Organisation for Research and Treatment of Cancer - EORTC

    lead NETWORK

Principal Investigators

  • A.N. Van Geel, MD · Daniel Den Hoed Cancer Center at Erasmus Medical Center

  • Ronald H. Blum, MD · NYU Langone Health

  • Thor A. Alvegard, MD, PhD · Lund University Hospital

  • Laurence H. Baker, DO, FACOI · University of Michigan Rogel Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1996-04-30
Primary Completion
2000-11-30

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00002764 on ClinicalTrials.gov