Topotecan and Radiation Therapy in Treating Patients With Solid Tumors or Lymphoma
NCT00002625 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2013-02-11
Summary
Phase I trial to study the effectiveness of topotecan and radiation therapy in treating patients who have solid tumors or lymphoma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Combining chemotherapy with radiation therapy may kill more cancer cells.
Conditions
- Esophageal Cancer
- Lung Cancer
- Lymphoma
Interventions
- DRUG
-
topotecan hydrochloride
- RADIATION
-
low-LET electron therapy
- RADIATION
-
low-LET photon therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
George Wilding, MD · University of Wisconsin, Madison
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1995-03-31
- Primary Completion
- 2000-04-30
- Completion
- 2000-09-30
Countries
- United States
Study Locations
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