A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection
NCT00000895 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 85
Last updated 2021-10-29
Summary
The purpose of this study is to determine if infection with Mycobacterium avium complex (MAC) occurs in other parts of the body before it is found in the blood. This study also evaluates the relationships between the amount of HIV in the blood, immune system functions, and the presence of MAC infection.
HIV-positive patients are at risk for MAC infection because their immune systems have been weakened by HIV. It is hoped that aggressive treatment with anti-HIV drugs may improve their immune systems enough to prevent against MAC.
Conditions
- Mycobacterium Avium-intracellulare Infection
- HIV Infections
Interventions
- DRUG
-
Nelfinavir mesylate
- DRUG
-
Nevirapine
- DRUG
Sponsors & Collaborators
-
National Institute of Allergy and Infectious Diseases (NIAID)
lead NIH
Principal Investigators
-
Rob Roy MacGregor
-
David Perlman
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Completion
- 2001-08-31
Countries
- United States
Study Locations
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