Lung Health Study II
NCT00000569 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1116
Last updated 2019-11-01
Summary
To determine if participants with chronic obstructive pulmonary disease, who were assigned to inhaled corticosteroids had a lower rate of decline in lung function and lower incidence of respiratory morbidity compared to participants assigned to placebo.
Conditions
- Lung Diseases
- Lung Diseases, Obstructive
- Chronic Obstructive Pulmonary Disease
Interventions
- DRUG
-
triamcinolone
1200 micrograms of triamcinolone in daily divided doses
- OTHER
-
Placebo
Placebo
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH - lead OTHER
Principal Investigators
-
John Connett · University of Minnesota
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 69 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1993-09-30
- Primary Completion
- 1999-05-31
- Completion
- 1999-05-31
More Related Trials
-
Diffuse Fibrotic Lung Disease
NCT00000596 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Tiotropium on Airway Diameter in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT02172391 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease
NCT01322594 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Feasibility of Ectoin® Inhalation Solution in Inflammatory Obstruction and Ageing of the Lung
NCT01225965 ·Status: COMPLETED ·Phase: NA
-
A Study to Investigate Using Inhaled Fexlamose to Treat Adult Participants Who Have Moderate to Severe COPD
NCT06731959 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
NCT05986318 ·Status: RECRUITING ·Phase: PHASE2
-
Theophylline in Chronic Obstructive Pulmonary Disease
NCT00299858 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Tiotropium Inhalation Capsules on Exercise Tolerance, Daily Activity and Dyspnoea in Patients With Chronic Obstructive Pulmonary Disease (COPD) Participating in 3 Weeks of Pulmonary Rehabilitation
NCT02172508 ·Status: TERMINATED ·Phase: PHASE4
-
Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)
NCT02105961 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis
NCT03903913 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
NCT06533553 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease
NCT00465959 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
NCT06603246 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
NCT04708782 ·Status: COMPLETED ·Phase: PHASE3
-
Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
NCT05255991 ·Status: COMPLETED ·Phase: PHASE3
-
Outcomes of Once-Daily ICS/LABA/LAMA + PRN Respiratory Therapy Treatments in Hospitalized Patients With COPD Exacerbations
NCT05292053 ·Status: COMPLETED ·Phase: PHASE4
-
Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis
NCT02657473 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough
NCT05660850 ·Status: COMPLETED ·Phase: PHASE2
-
TD-1058 First-In-Human Study in Healthy Subjects and Subjects With Idiopathic Pulmonary Fibrosis
NCT04589260 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Lebrikizumab (RO5490255) in Participants With Severe Oral Corticosteroids (OCS) Dependent Asthma
NCT01987492 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Effects of the Drug (SB-656933-AAA) on the Body After a Single Dose in Subjects Who Have Inhaled Ozone
NCT00551811 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
NCT07201051 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of Biomarkers of Airway Inflammation (0000-128)
NCT00869596 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial to Evaluate the Efficacy and Safety of Faropenem Medoxomil In the Treatment of Chronic Bronchitis
NCT00255983 ·Status: TERMINATED ·Phase: PHASE3
-
A Study in Patients With Non-cystic Fibrosis Bronchiectasis to Test How Well Different Doses of BI 1323495 Are Tolerated and How BI 1323495 Affects Biomarkers of Inflammation
NCT04656275 ·Status: TERMINATED ·Phase: PHASE1