Effect of Tiotropium on Airway Diameter in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT02172391 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 81
Last updated 2018-08-31
Summary
Trial to investigate the acute and chronic effect of tiotropium therapy on airway diameter in COPD patients as measured by inspiratory capacity (IC).
Conditions
- Pulmonary Disease, Chronic Obstructive
Interventions
- DRUG
-
Tiotropium inhalation powder capsules
- DRUG
-
Placebo inhalation powder capsules
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-11-30
- Primary Completion
- 2001-08-31
More Related Trials
-
Tiotropium Induced Bronchodilation in Lung CT Scored Emphysema
NCT00570544 ·Status: COMPLETED
-
Efficacy of Tiotropium in Patients of African Descent With Chronic Obstructive Pulmonary Disease
NCT00106821 ·Status: COMPLETED ·Phase: PHASE4
-
Dynamic Hyperinflation and Tiotropium
NCT00569270 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease
NCT01072396 ·Status: COMPLETED ·Phase: PHASE4
-
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.
NCT01533935 ·Status: COMPLETED ·Phase: PHASE3
-
Airway Effects of Tiotropium in Patients With COPD
NCT02683668 ·Status: COMPLETED ·Phase: PHASE3
-
Tiotropium In Exercise
NCT00525512 ·Status: COMPLETED ·Phase: PHASE4
-
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients
NCT01533922 ·Status: COMPLETED ·Phase: PHASE3
-
Tiotropium Respimat Pharmacokinetic Study in COPD
NCT01222533 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Tiotropium (Spiriva) on Exercise Tolerance in COPD Patients
NCT00274508 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Lung Deposition Rate and Distribution Pattern of Tiotropium Via HandiHalerTM in Healthy Subjects and Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT02172456 ·Status: COMPLETED ·Phase: PHASE3
-
12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD
NCT00240435 ·Status: COMPLETED ·Phase: PHASE3
-
Mechanisms of Dyspnea Relief During Exercise in COPD Patients Following Treatment With Tiotropium (Spiriva)
NCT00274027 ·Status: COMPLETED ·Phase: PHASE3
-
A Randomised, Double-blind, Placebo-controlled, 12 Week Trial to Evaluate the Effect of Tiotropium Inhalation Capsules (Spiriva) on the Magnitude of Exercise, Measured Using an Accelerometer, in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT00144326 ·Status: COMPLETED ·Phase: PHASE3
-
Tiotropium / Respimat One-Year Study
NCT00168831 ·Status: COMPLETED ·Phase: PHASE3
-
The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT00870896 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Tiotropium Respimat Administration With and Without Aerochamber Disease (COPD)
NCT04999930 ·Status: COMPLETED ·Phase: NA
-
Bioequivalence Study of Tiotropium 18 μg Inhalation Powder, Hard Capsule With Spiriva®Handihaler® 18 μg Inhalation Powder, Hard Capsule in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT05986591 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Inhalative Doses of BI 1744 CL in Fixed Dose Combination With Tiotropium Bromide in Healthy Male Volunteers
NCT02259959 ·Status: COMPLETED ·Phase: PHASE1
-
Tiotropium (Spiriva) Rehabilitation Study
NCT00274521 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability and Pharmacokinetics of Tiotropium in Cystic Fibrosis Patients
NCT02172534 ·Status: COMPLETED ·Phase: PHASE1
-
Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2
NCT01662986 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacokinetics and Safety Comparison of Tiotropium Inhalation Powder Administered as the Bromide Salt From Hard Polyethylene Capsule Via the HandiHaler® 2 and Spiriva® HandiHaler® in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT02242266 ·Status: COMPLETED ·Phase: PHASE2
-
Tiotropium (18mcg) in Chronic Obstructive Pulmonary Disease (COPD) Patients With a Respiratory Infection
NCT01483625 ·Status: COMPLETED ·Phase: PHASE4
-
Tiotropium Bromide in Cystic Fibrosis
NCT01179347 ·Status: COMPLETED ·Phase: PHASE3