Asymptomatic Cardiac Ischemia Pilot (ACIP) Study

Summary

To assess the feasibility of and test the methodology for a full-scale clinical trial of therapies for asymptomatic cardiac ischemia.

Conditions

• Cardiovascular Diseases
• Coronary Disease
• Heart Diseases
• Myocardial Ischemia

Interventions

DRUG

atenolol

DRUG

nifedipine

DRUG

diltiazem

DRUG

isosorbide dinitrate

PROCEDURE

coronary artery bypass coronary artery bypass

PROCEDURE

angioplasty, transluminal, percutaneous coronary

Sponsors & Collaborators

• National Heart, Lung, and Blood Institute (NHLBI)

  lead NIH

Principal Investigators

• Jerome Cohen · St. Louis University

• Richard Davies · University of Ottawa

• John Deanfield · St. Bartholomew's Hospital, University of London

• Mark Ketterer · Henry Ford Hospital

• Genell Knatterud

• Hiltrud Mueller · Montefiore Medical Center

• Pamela Ouyang · Johns Hopkins University

• Carl Pepine · University of Florida

• Craig Pratt · Baylor College of Medicine

• William Rogers · University of Alabama at Birmingham

• Andrew Selwyn · Brigham and Women's Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

1990-11-30

Completion

1997-06-30