News Related to Immunomodulatory Therapies

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Influenza A-Associated Acute Necrotizing Encephalitis With Complete Recovery in 19-Month-Old

Aug 13, 2026

A 19-month-old girl with influenza A (H1N1)-associated acute necrotizing encephalitis made a complete neurological recovery despite a severity score of 6. Multimodal immunomodulatory therapy including IVIG, corticosteroids, anakinra, and plasma exchange led to rapid decline in blood cytokine levels. The case underscores early recognition and targeted treatment in young children.

Pediatric Enterovirus Meningitis Shows Low Long-Term Risk, Global Burden Remains High

Apr 01, 2026

A study finds most children with enterovirus meningitis have favorable long-term outcomes, with only 8.9% experiencing adverse sequelae. Meanwhile, global data shows 259,000 meningitis deaths in 2023, with children under 5 accounting for over one-third of fatalities. Non-polio enteroviruses were the leading cause of meningitis cases worldwide.