News Related to Hormone Replacement Therapy

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Estrogen-Only HRT After RRBO Linked to Lower Breast Cancer Risk in BRCA1 Carriers

May 20, 2026

Estrogen-only hormone replacement therapy after risk-reducing bilateral oophorectomy was associated with lower breast cancer risk in women with BRCA1 pathogenic variants. In 919 women followed for an average of 8.8 years, incident breast cancer was lower among HRT users than nonusers.

FDA Removes Black Box Warning from Menopausal Hormone Therapy Products

Feb 13, 2026

The FDA has approved labeling changes to six menopausal hormone therapy products, removing boxed warnings related to cardiovascular disease, breast cancer, and probable dementia that had been in place since 2003.