News Related to Drug-Regulated Off-Switch PPI CAR

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CAR T-Cell Therapy Advances: Remote-Control Systems and Glioblastoma Applications

Feb 26, 2026

Researchers have developed a remote-controlled CAR T-cell therapy that can be switched off on demand using venetoclax, while new engineering strategies aim to overcome barriers in treating glioblastoma and other solid tumors.

Researchers Advance CAR T-Cell Safety with Remote Control and Risk Prediction Studies

Feb 25, 2026

New research addresses CAR T-cell therapy safety through a venetoclax-controlled on-off switch and a prospective study identifying neurotoxicity risk markers in pediatric patients with acute lymphoblastic leukemia.