News Related to TIGIT

Related coverage linked through entity extraction aliases.

CD27 Expression Identified as Key Marker for Monitoring Treg Therapy Efficacy

Jun 25, 2026

Research has identified CD27 expression as a potential biomarker for monitoring regulatory T cell (Treg) induction efficacy in clinical trials. Studies show CD27 marks memory-like Tregs with superior suppressive capacity, correlating with immune regulation in type 1 diabetes patients. Treg-based tolerance restoration is emerging as a therapeutic strategy for autoimmune diseases and transplantation.

Multiple Studies Highlight Differing Immunotherapy Outcomes in Advanced NSCLC

Jun 14, 2026

Multiple recent studies evaluate different immunotherapy approaches for advanced NSCLC, including long-term benefits for nivolumab plus ipilimumab with chemotherapy in PD-L1-negative tumors, limited advantages from PD-(L)1 rechallenge strategies, and early positive signals from combining TIGIT and PD-1 inhibitors in PD-L1-high patients.

Compugen Reports Q1 2026 Financial Results, Provides Pipeline Update

Jun 02, 2026

Compugen reported a Q1 2026 net loss of $7.7 million with approximately $134.9 million in cash, expecting runway into 2029. The COM701 MAIA-ovarian trial is enrolling across the U.S., Israel, and France, with interim analysis expected by Q1 2027. Partner AstraZeneca is advancing rilvegostomig across 11 Phase 3 trials.