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CAR T-Cell Therapies Target BCMA and Alternative Antigens in Multiple Myeloma

Feb 28, 2026

New CAR T-cell approaches targeting BCMA and CD19 simultaneously show encouraging early results, while researchers develop control strategies for CAR-T therapies including antibody-drug conjugates.

Proteasome Inhibitor Restores BCMA Expression After CAR T-Cell Therapy Failure in Myeloma

Feb 18, 2026

Preclinical and early clinical data show carfilzomib can restore BCMA expression on myeloma cells after CAR T-cell therapy failure, with 6 of 10 patients experiencing renewed clinical responses in a small study.