AI-powered biochip detects genetic markers in 20 minutes
Scientists at NTU Singapore developed an AI-powered biochip that detects multiple microRNA biomarkers in 20 minutes. The platform achieved more than 99 per cent accuracy in test channels.
microRNA
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Two Experimental ALS Therapies Report Positive Safety Data from Early-Stage Trials
PrimeC, an oral combination therapy, showed safety and signals of clinical benefit in a phase 2b trial, while PLL001, a gut-targeting therapy, demonstrated positive safety and tolerability in a phase I/II study for amyotrophic lateral sclerosis.
RNA-Targeting Small Molecules Gain Momentum as Drug Discovery Frontier
Pharmaceutical companies are increasingly partnering with biotechs developing RNA-targeting small molecules, driven by advances in RNA structural biology and the success of drugs like Roche's Evrysdi. The approach aims to address "undruggable" targets while offering oral availability advantages.
Drug Discovery Shifts to New Targets: RNA, Cell Surface Proteins, and Sequence-Based AI
Drug discovery is expanding beyond traditional protein targets to include RNA-targeting small molecules, cell surface proteins, and sequence-based AI platforms capable of screening billions of candidates across the entire genome.