News Related to Interleukin-5

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Tezepelumab Reduces Oral Corticosteroid Dependence in Severe Asthma, Case Report Shows Functional Recovery

Jun 05, 2026

A placebo-controlled trial shows tezepelumab significantly reduces oral corticosteroid dependence in severe asthma, with patients achieving nearly three times the odds of reduction versus placebo. A separate case report documents dramatic functional recovery in an elderly patient who switched from mepolizumab to tezepelumab after inadequate response.

European Commission Approves Exdensur for Severe Asthma and Chronic Rhinosinusitis

Feb 17, 2026

The European Commission has approved GSK's Exdensur (depemokimab) as the first ultra-long-acting biologic for severe asthma with type 2 inflammation and chronic rhinosinusitis with nasal polyps, offering twice-yearly dosing based on positive phase 3 trial results.