News Related to Cytotoxic T-Lymphocyte-Associated Protein 4

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Oral Listeria Vaccine Enhances Immunotherapy Response in Colorectal Cancer

Feb 24, 2026

Researchers at Stony Brook University developed an oral vaccine using modified Listeria monocytogenes that generates anti-tumor immune responses in the gut and significantly improves colorectal cancer control when combined with checkpoint inhibitors.

CStone Pharmaceuticals Receives FDA Clearance for CS2009 Phase II Trial in Solid Tumors

Feb 16, 2026

CStone Pharmaceuticals has received FDA clearance for its IND application to initiate a Phase II trial of CS2009, a trispecific antibody targeting PD-1, VEGFA, and CTLA-4, in patients with advanced solid tumors across nine cancer indications.