NCT03975647 A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT03914755 A Safety, Tolerability, and Pharmacokinetic Study of Tucatinib in Healthy Japanese and Caucasian Subjects Status COMPLETED Phase PHASE1
NCT03826602 A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin Status COMPLETED Phase PHASE1
NCT03777761 Effects of Tucatinib on Cardiac Repolarization in Healthy Participants Status COMPLETED Phase PHASE1
NCT03758339 A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants Status COMPLETED Phase PHASE1
NCT03723395 A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib Status COMPLETED Phase PHASE1
NCT03722823 A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects Status COMPLETED Phase PHASE1
NCT03501979 Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD Status TERMINATED Phase PHASE2
NCT03424473 Expanded Access Use of Tucatinib for HER2+ Metastatic Breast Cancer Status NO_LONGER_AVAILABLE Phase N/A
NCT03297606 Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) Status RECRUITING Phase PHASE2
NCT03043313 Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Status COMPLETED Phase PHASE2
NCT02892123 Trial of ZW25 (Zanidatamab) in Patients With Advanced HER2-expressing Cancers Status COMPLETED Phase PHASE1
NCT02614794 A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer Status COMPLETED Phase PHASE2
NCT02025192 A Study of Tucatinib (ONT-380) Combined With Capecitabine and/or Trastuzumab in Patients With HER2+ Metastatic Breast Cancer Status COMPLETED Phase PHASE1