NCT05356897 Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study Status WITHDRAWN Phase PHASE2
NCT05325632 Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab Status RECRUITING Phase PHASE2
NCT05323955 Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinib Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05319873 Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05318339 A Study of Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma Status UNKNOWN Phase PHASE2
NCT05253651 A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer Status RECRUITING Phase PHASE3
NCT05218148 SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma Status NOT_YET_RECRUITING Phase PHASE2
NCT05207722 CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma Status TERMINATED Phase PHASE1/PHASE2
NCT05193292 Camrelizumab Combined With Trastuzumab and Chemotherapy in Patients With HER2-positive Advanced Colorectal Cancer Status UNKNOWN Phase PHASE2
NCT05189067 Efficacy and Safety of Adjuvant Docetaxel and Trastuzumab in Stage I HER2-positive Breast Cancer Status UNKNOWN Phase PHASE2/PHASE3
NCT05188313 TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer Status RECRUITING Phase PHASE3
NCT05187182 CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer Status RECRUITING Phase PHASE1
NCT05180006 Impact of Neoadjuvant Immunotherapy in Early Stage Breast Cancer Before Standard Therapy Status TERMINATED Phase PHASE2
NCT05170256 Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients Status UNKNOWN Phase PHASE2
NCT05152147 A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05132582 A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05113251 Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05091528 A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers Status TERMINATED Phase PHASE1/PHASE2