NCT05180006 Impact of Neoadjuvant Immunotherapy in Early Stage Breast Cancer Before Standard Therapy Status TERMINATED Phase PHASE2
NCT05170256 Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients Status UNKNOWN Phase PHASE2
NCT05152147 A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05132582 A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05113251 Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05091528 A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers Status TERMINATED Phase PHASE1/PHASE2
NCT05081609 A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05076695 Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer Status UNKNOWN Phase PHASE2
NCT05063786 Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05062889 Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients Status SUSPENDED Phase PHASE2
NCT05041842 Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05020860 Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer Status RECRUITING Phase PHASE2
NCT05002127 A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) Status ACTIVE_NOT_RECRUITING Phase PHASE2/PHASE3
NCT04993014 Circulating Tumor Cells and Treatment De-escalation After Neoadjuvant Therapy for HER2 Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04973319 Trastuzumab Combined With Pertuzumab for Adjuvant Treatment of Breast Cancer After Neoadjuvant Therapy Status NOT_YET_RECRUITING Phase PHASE3
NCT04962425 Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients Status UNKNOWN Phase N/A
NCT04961307 Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab Status UNKNOWN Phase N/A
NCT04957212 Comparing Efficacy and Safety Between Pertuzumab® and Perjeta® in Neoadjuvant Treatment of HER2+ Breast Cancer Status COMPLETED Phase PHASE3
NCT04928261 Evaluating 6-months of HER2-targeted Therapy in Patients With HER2 Positive Early-stage Breast Cancer That Achieve a Pathological Complete Response to Neoadjuvant Systemic Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE4