NCT04739761 A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04704934 Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04704661 Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04644237 Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC) Status COMPLETED Phase PHASE2
NCT04639219 A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04616560 Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor Status RECRUITING Phase PHASE1/PHASE2
NCT04585958 Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer Status RECRUITING Phase PHASE1
NCT04556773 A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04553770 Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04539938 A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer Status COMPLETED Phase PHASE2
NCT04538742 A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04494425 Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04482309 A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04420598 DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease Status COMPLETED Phase PHASE2
NCT04379596 Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) Status RECRUITING Phase PHASE2
NCT04294628 Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04014075 DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02) Status COMPLETED Phase PHASE2
NCT03742102 A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT03523585 DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] Status COMPLETED Phase PHASE3
NCT03523572 Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer Status COMPLETED Phase PHASE1