NCT04616560 Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma Status SUSPENDED Phase PHASE2
NCT04585958 Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer Status RECRUITING Phase PHASE1
NCT04556773 A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04553770 Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04539938 A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer Status COMPLETED Phase PHASE2
NCT04538742 A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04494425 Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04482309 A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04420598 DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease Status COMPLETED Phase PHASE2
NCT04379596 Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) Status RECRUITING Phase PHASE2
NCT04294628 Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04014075 DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02) Status COMPLETED Phase PHASE2
NCT03742102 A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT03523585 DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] Status COMPLETED Phase PHASE3
NCT03523572 Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer Status COMPLETED Phase PHASE1
NCT03505710 DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung Cancer Status TERMINATED Phase PHASE2
NCT03424005 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer Status RECRUITING Phase PHASE1/PHASE2
NCT03334617 Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE2