NCT07549646 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT07110246 Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas Status RECRUITING Phase PHASE2
NCT06475989 Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer Status RECRUITING Phase PHASE3
NCT04940052 Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04116541 A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. Status RECRUITING Phase PHASE2
NCT03825289 Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer Status TERMINATED Phase PHASE1
NCT03363217 Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT03149029 Abbreviated MAPK Targeted Therapy Plus Pembrolizumab in Melanoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT02642042 Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT02465060 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT02079740 Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT01989585 Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT01682083 Dabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD). Status COMPLETED Phase PHASE3