NCT07549646 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT07468071 Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments Status RECRUITING Phase PHASE1/PHASE2
NCT07440290 DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. Status RECRUITING Phase PHASE2/PHASE3
NCT07110246 Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas Status RECRUITING Phase PHASE2
NCT06475989 Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer Status RECRUITING Phase PHASE3
NCT05358249 Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05180825 Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy Status RECRUITING Phase PHASE2
NCT04940052 Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04675710 Pembrolizumab, Dabrafenib, and Trametinib Before Surgery for the Treatment of BRAF-Mutated Anaplastic Thyroid Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04485559 Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) Status RECRUITING Phase PHASE1
NCT04238624 Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04116541 A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. Status RECRUITING Phase PHASE2
NCT04111458 A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation) Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT03975829 Pediatric Long-Term Follow-up and Rollover Study Status ACTIVE_NOT_RECRUITING Phase PHASE4
NCT03825289 Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer Status TERMINATED Phase PHASE1
NCT03363217 Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. Status ACTIVE_NOT_RECRUITING Phase PHASE2