Secukinumab

Drug

Related News

Bimekizumab Durable Improvements in Psoriasis Over 3 Years in BE RADIANT Trial

In the BE RADIANT phase 3b trial, bimekizumab provided greater and durable improvements in patient-reported symptoms, skin clearance, and quality of life over 3 years compared with secukinumab in moderate to severe plaque psoriasis. At week 4, significantly more patients on bimekizumab achieved complete absence of itching, skin pain, and scaling. The benefits were sustained through 3 years, including after patients switched from secukinumab.

Phase IIb Trial Shows Low-Dose IL-2 Effective in SLE

A phase IIb trial demonstrated that low-dose IL-2 therapy produced dose-dependent improvements in SLE patients, with 69.7% achieving SRI-4 response at the highest dose versus 23.5% on placebo. A separate systematic review found IL-17 inhibitors remain potential SLE treatment options, though efficacy data are limited.

Related Clinical Trials

NCT ID Title Status Phase
NCT07489573

Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa

RECRUITING PHASE4
NCT07352566

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

NOT_YET_RECRUITING PHASE4
NCT07138898

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

RECRUITING PHASE2
NCT06905288

Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.

RECRUITING
NCT06751238

Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

RECRUITING PHASE1
NCT06331312

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

ACTIVE_NOT_RECRUITING PHASE3
NCT05622708

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

ACTIVE_NOT_RECRUITING PHASE4
NCT04179175

Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

COMPLETED PHASE3