NCT04419181 Feasibility of Chemotherapy De-escalation in Early-Stage HER2 Positive Breast Cancer Status WITHDRAWN Phase PHASE2
NCT04398914 Pyrotinib, Trastuzumab, Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04337658 Anti-HER2 Therapy + Fulvestrant/Capecitabine in Women With HR+, HER2+, Non-visceral Metastases Stage IV Breast Cancer Status NOT_YET_RECRUITING Phase PHASE3
NCT04329065 Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer Status RECRUITING Phase PHASE2
NCT04266249 CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04253561 Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients Status COMPLETED Phase PHASE1
NCT04208178 Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04197687 TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery Status UNKNOWN Phase PHASE2
NCT04193059 Study Comparing EC-T Verses PCb in the Adjuvant Chemotherapy of Non-triple Negative Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04188548 A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04172259 ACHP-THP vs EC-THP as Neoadjuvant Therapy for HER2-positive EBC Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04158258 A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin America Status ACTIVE_NOT_RECRUITING Phase N/A
NCT04108858 Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer Status TERMINATED Phase PHASE1/PHASE2
NCT03988036 A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1) Status COMPLETED Phase PHASE2
NCT03894007 Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer Status TERMINATED Phase PHASE2
NCT03878524 Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial Status TERMINATED Phase PHASE1
NCT03820141 Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT03811418 A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer Status WITHDRAWN Phase PHASE3
NCT03747120 Neoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab [IIT2018-04-MCARTHUR-NEOHP] Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT03726879 A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer Status COMPLETED Phase PHASE3