NCT06868277 A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06863402 Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype Status RECRUITING Phase PHASE2
NCT06860386 Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCC Status SUSPENDED Phase PHASE2
NCT06846268 Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer Status RECRUITING Phase PHASE2
NCT06845319 NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients Status RECRUITING Phase PHASE2
NCT06843447 A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003) Status RECRUITING Phase PHASE1/PHASE2
NCT06841354 A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011) Status RECRUITING Phase PHASE3
NCT06829199 A Clinical Study of Boserolimab (MK-5890) With Pembrolizumab and Chemotherapy in People With Early Triple-Negative Breast Cancer (MK-5890-003) Status WITHDRAWN Phase PHASE2
NCT06822543 A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer) Status RECRUITING Phase PHASE2
NCT06814067 Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma Status NOT_YET_RECRUITING Phase PHASE2
NCT06809140 Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer Status RECRUITING Phase PHASE2
NCT06806852 A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT06797635 Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03) Status RECRUITING Phase PHASE2
NCT06797297 A Study to Evaluate the Efficacy and Safety of IBI363 Monotherapy Compared to Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal or Acral Melanoma Who Had Not Previously Received Systemic Therapy Status RECRUITING Phase PHASE2
NCT06795412 Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT06793761 A Phase II Study to Evaluate the Efficacy and Safety of Salvage Preoperative PD-1 Inhibitor Combined with Chemotherapy Neoadjuvant Therapy in Recurrent and Metastatic LPSCC/HPSCC Status NOT_YET_RECRUITING Phase PHASE2
NCT06793215 A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06780111 Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) Status RECRUITING Phase PHASE1/PHASE2
NCT06772623 Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations Status RECRUITING Phase PHASE1/PHASE2