NCT06390839 Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amplification (MATCH - Subprotocol Z1C) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT06380751 Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer Status RECRUITING Phase PHASE3
NCT06338644 Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. Status NOT_YET_RECRUITING Phase N/A
NCT06188520 A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT06126276 Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial) Status RECRUITING Phase PHASE2
NCT06086340 Study to Compare Overall Survival in Medicare Patients With Metastatic Breast Cancer Treated With a Medicine Called Palbociclib in Combination With Aromatase Inhibitor and Aromatase Inhibitor by Itself. Status COMPLETED Phase N/A
NCT06076772 Palbociclib Induced Neutropenia; Risk Factors and Treatment Outcome in Metastatic Breast Cancer Patients Status NOT_YET_RECRUITING Phase N/A
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) Status RECRUITING Phase PHASE3
NCT06065592 Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms Status RECRUITING Phase PHASE1
NCT06003114 A Study to Understand the Use of Palbociclib in Canadian Patients With Breast Cancer That Has Spread to Other Organs Status COMPLETED Phase N/A
NCT05949424 OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults Status NOT_YET_RECRUITING Phase PHASE4
NCT05935748 Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc) Status TERMINATED Phase PHASE2
NCT05867251 Study of AVZO-021 in Patients With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05865132 Palbociclib Combined With Afatinib for Advanced Squamous Carcinoma of Esophagus or Gastroesophageal Junction Status RECRUITING Phase PHASE2
NCT05768139 First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05766410 A Randomized Study Comparing the Immune Modulation Effect of Ribociclib, Palbociclib, and Abemaciclib in ER+/HER2- EBC Status RECRUITING Phase PHASE2
NCT05759949 First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors Status COMPLETED Phase PHASE1
NCT05725200 Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer Status RECRUITING Phase PHASE2