NCT06692491 Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS Status NOT_YET_RECRUITING Phase PHASE2
NCT06670196 A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06630325 A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer Status TERMINATED Phase PHASE2
NCT06618287 A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT06574347 Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC. Status RECRUITING Phase PHASE2
NCT06538038 Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients Status RECRUITING Phase N/A
NCT06532149 ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung Cancer Status RECRUITING Phase N/A
NCT06507306 A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies Status RECRUITING Phase PHASE1
NCT06486142 EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study Status RECRUITING Phase PHASE3
NCT06436144 Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC Status NOT_YET_RECRUITING Phase PHASE2
NCT06417814 A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06383728 Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell Carcinoma Status RECRUITING Phase PHASE2
NCT06362980 A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations Status RECRUITING Phase PHASE1
NCT06350097 Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06323148 Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022) Status NOT_YET_RECRUITING Phase PHASE3
NCT06319950 High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases Status NOT_YET_RECRUITING Phase PHASE2
NCT06304441 Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer Status RECRUITING Phase NA
NCT06303167 Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT06206850 Neo-Bio-ADAURA: a Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib Status RECRUITING Phase PHASE2
NCT06194448 To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE2