NCT06362980 A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations Status RECRUITING Phase PHASE1
NCT06350097 Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06323148 Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022) Status NOT_YET_RECRUITING Phase PHASE3
NCT06319950 High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases Status NOT_YET_RECRUITING Phase PHASE2
NCT06304441 Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer Status RECRUITING Phase NA
NCT06303167 Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT06206850 Neo-Bio-ADAURA: a Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib Status RECRUITING Phase PHASE2
NCT06194448 To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT06142617 A Prospective Study of Pembrolizumab Combining Chemotherapy in Advanced NSCLC Patients With EGFR Exon 21 Point Mutation. Status NOT_YET_RECRUITING Phase PHASE2
NCT06093503 Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein Status WITHDRAWN Phase PHASE3
NCT06067776 Osimertinib, Cetuximab, and Tucatinib for the Treatment of EGFR-Mutant Stage IV or Recurrent Non-small Lung Cell Cancer Status NOT_YET_RECRUITING Phase PHASE1
NCT06032936 BBP-398 in Combination With Osimertinib in Locally Advanced or Metastatic NSCLC Patients With EGFR Mutations Status TERMINATED Phase PHASE1
NCT06018688 Osimertinib Combined With Aspirin Neoadjuvant Therapy for Resectable EGFR Mutated NSCLC Patients. Status NOT_YET_RECRUITING Phase PHASE2
NCT06014827 Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma Status RECRUITING Phase PHASE2
NCT05954871 Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer Status COMPLETED Phase PHASE1
NCT05948813 TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases Status RECRUITING Phase PHASE2
NCT05834348 A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway. Status COMPLETED Phase N/A
NCT05816252 A Study of SKB264 (MK-2870; Sac-TMT) for the Treatment of Participants With Advanced or Metastatic Non-small Cell Lung Cancer (SKB264-II-04) (MK-2870-003) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05801029 A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05785741 A Study of DB-1310 in Advanced/Metastatic Solid Tumors Status RECRUITING Phase PHASE1/PHASE2