NCT05564377 Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial Status RECRUITING Phase PHASE2
NCT05554328 Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial Status RECRUITING Phase PHASE2
NCT05536128 Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor Status RECRUITING Phase PHASE2
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma Status RECRUITING Phase PHASE2
NCT05522491 Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer Status NOT_YET_RECRUITING Phase PHASE2
NCT05501548 Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer Status TERMINATED Phase PHASE2
NCT05498272 Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations Status RECRUITING Phase PHASE2
NCT05485766 Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer Status RECRUITING Phase PHASE2
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE4
NCT05432791 Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working Status ACTIVE_NOT_RECRUITING Phase PHASE2/PHASE3
NCT05411094 Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer Status RECRUITING Phase PHASE1
NCT05405309 RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic Leukemia Status TERMINATED Phase PHASE1/PHASE2
NCT05379972 Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05340413 Predicting Olaparib Sensitivity in Patients With Unresectable Locally Advanced/Metastatic HER2-negative Breast Cancer. Status COMPLETED Phase PHASE2
NCT05332561 Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE) Status RECRUITING Phase PHASE2