NCT04298021 DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04269200 Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04239014 A Study to Evaluate the Effectiveness and Tolerability of a Second Maintenance Treatment in Participants With Ovarian Cancer, Who Have Previously Received Polyadenosine 5'Diphosphoribose [Poly (ADP Ribose)] Polymerase Inhibitor (PARPi) Treatment. Status WITHDRAWN Phase PHASE2
NCT04236414 Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours Status COMPLETED Phase PHASE1
NCT04209686 Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04197713 Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04191135 Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009) Status COMPLETED Phase PHASE2
NCT04152941 Real-life Data of Olaparib in Relapsed Ovarian Cancers Patients Status COMPLETED Phase N/A
NCT04123366 Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04090567 Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer Status RECRUITING Phase PHASE2
NCT04086485 Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET) Status RECRUITING Phase PHASE1/PHASE2
NCT04076579 Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma Status COMPLETED Phase PHASE2
NCT04065269 ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no Loss Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04053322 Durvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients. Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04042831 Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04038502 Carboplatin or Olaparib for BRcA Deficient Prostate Cancer Status RECRUITING Phase PHASE2
NCT04034927 Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04005690 Targeted Pathway Inhibition in Patients With Pancreatic Cancer Status RECRUITING Phase EARLY_PHASE1