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FDA Approves Three New Targeted Therapies for Advanced Prostate Cancer

Jun 16, 2026

The FDA has approved three new targeted therapies for different stages of advanced prostate cancer: Truqap for PTEN-deficient tumors, rucaparib for BRCA-mutated castration-resistant disease, and Akeega for BRCA2-mutated castration-sensitive cancer.

PARP inhibitors remain strongest in BRCA-mutant tumors as labels narrow

Apr 22, 2026

PARP inhibitors remain strongest in BRCA1/2-altered tumors as use beyond that group has been uneven. In June 2025, the FDA narrowed Zejula’s first-line ovarian maintenance indication to HRD-positive tumors only.