NCT04716933 Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)-China Extension Study Status COMPLETED Phase PHASE3
NCT04704219 Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61) Status COMPLETED Phase PHASE2
NCT04700072 Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02) Status COMPLETED Phase PHASE1/PHASE2
NCT04676412 Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Nonsmall Cell Lung Cancer (NSCLC) [MK-7902-007/E7080-G000-314/LEAP-007] - China Extension Study Status COMPLETED Phase PHASE3
NCT04662710 Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015) Status COMPLETED Phase PHASE3
NCT04656249 Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer Status COMPLETED Phase PHASE2
NCT04627012 Lenvatinib Combined Anti-PD1 Antibody for the Advanced Hepatocellular Carcinoma Status COMPLETED Phase N/A
NCT04626518 Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03) Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04626479 Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A) Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04618367 HAIC Combined With Lenvatinib and Sintilimab for Hepatocellular Carcinoma With PVTT Status COMPLETED Phase NA
NCT04586231 A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04560751 TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma (Prolong) Status UNKNOWN Phase N/A
NCT04542837 The Study of KN046 in Combination With Lenvatinib in Advanced Hepatocellular Carcinoma Status COMPLETED Phase PHASE2
NCT04522323 A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04519151 Pembrolizumab and Lenvatinib for Platinum- Sensitive Recurrent Ovarian Cancer Status RECRUITING Phase PHASE2
NCT04490694 TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma Status UNKNOWN Phase PHASE2
NCT04447755 A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080) Status COMPLETED Phase PHASE2
NCT04444167 A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma Status COMPLETED Phase PHASE1/PHASE2